The Australian Journal of Mathematical Analysis and Applications

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ISSN 1449-5910  


Paper Information

Paper Title:

Optimal Control Analysis of HIV/AIDS Epidemic Model with an Antiretroviral Treatment


U. Habibah and R. A. Sari

Mathematics Department and Reseach Group of Biomathematics,
Faculty of Mathematics and Natural Science,
Brawijaya University, Jl. Veteran Malang 65145,


A mathematical model of HIV/AIDS is governed by a system of ordinary differential equations in the presence of an antiretroviral treatment (ARV). The theory of optimal control is applied to an epidemic model of HIV/AIDS which an ARV is used as a control strategy in order to prevent the spread of HIV/AIDS. The optimality system is derived by applying the Pontryagin's Minimum Principle. We analyze the boundedness and positivity of solutions, and an existence of the optimal control. Numerical simulations are conducted to obtain numerical solution of the optimally system.

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